Bacteriophage Prevents Alcoholic Liver Disease | Zendy

Melis Çolakoğlu | Zendy; Jing Xue | Zendy; Mirko Trajkovski | Zendy

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Bacteriophage Prevents Alcoholic Liver Disease

Author(s) -

Melis Çolakoğlu,

Jing Xue,

Mirko Trajkovski

Publication year - 2020

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2019.12.034

Subject(s) - alcoholic hepatitis , biology , alcoholic liver disease , bacteriophage , disease , enterococcus faecalis , microbiology and biotechnology , liver disease , bacteria , virology , liver injury , hepatitis , immunology , gastroenterology , medicine , escherichia coli , genetics , cirrhosis , pharmacology , gene , biochemistry , staphylococcus aureus

Alcoholic hepatitis is a severe alcohol-associated liver disease with minimal treatment options. A recent study by Duan et al. uncovers that the exotoxin-secreting gut bacterium Enterococcus faecalis is a critical contributor to alcoholic hepatitis. This bacterium can now be eliminated with a bacteriophage, suggesting a new way to treat this life-threatening disease.

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