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Multisystem Toxicity in Cancer: Lessons from NASA’s Countermeasures Program
Author(s) -
Jessica M. Scott,
Lianne B. Dolan,
Larry Norton,
John B. Charles,
Lee W. Jones
Publication year - 2019
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2019.10.024
Subject(s) - biology , spaceflight , cancer , cancer therapy , engineering , aerospace engineering , genetics
Astronauts and cancer patients are subject to similar multisystem physiological toxicities. Over the past sixty years, NASA developed a state-of-the-art countermeasures program (CMP) to characterize and mitigate the physiological consequences of spaceflight. Here, we propose a NASA-modeled CMP to elucidate and abrogate physiological toxicities in patients with cancer.

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