Open AccessThe Immune-Mind Connection
Author(s) -
Saiyu Hang,
Jun R. Huh
Publication year - 2019
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2019.10.012
Subject(s) - biology , immune system , anxiety , neuroscience , microbiology and biotechnology , immunology , psychology , psychiatry
How does stress promote anxiety? In this issue of Cell, Fan et al. report that immune cells have a direct role in this process. They show that chronic stress promotes mitochondrial fission in CD4 + T cells, causing increased synthesis of xanthine, which acts on the brain and induces anxiety-like behaviors.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom