A Microtubule-Myelination Connection | Zendy

Antonina RollMecak | Zendy

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A Microtubule-Myelination Connection

Author(s) -

Antonina RollMecak

Publication year - 2019

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2019.08.046

Subject(s) - microtubule , biology , microbiology and biotechnology , cytoarchitecture , oligodendrocyte , golgi apparatus , microtubule organizing center , myelin , neuroscience , centrosome , cell , genetics , endoplasmic reticulum , central nervous system , cell cycle

Microtubules are critical for the extension of oligodendrocyte processes and myelin deposition, yet our knowledge of their microtubule biogenesis is limited. In this issue of Cell, Fu et al. (2019) identify an oligodendrocyte-enriched microtubule regulator that promotes microtubule growth from Golgi outposts and controls myelin sheath elongation, linking microtubule cytoarchitecture and myelination in the CNS.

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