Crenarchaeal 3D Genome: A Prototypical Chromosome Architecture for Eukaryotes | Zendy

Xu Feng | Zendy; Qihong Huang | Zendy; Qunxin She | Zendy

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Crenarchaeal 3D Genome: A Prototypical Chromosome Architecture for Eukaryotes

Author(s) -

Xu Feng,

Qihong Huang,

Qunxin She

Publication year - 2019

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2019.08.045

Subject(s) - biology , compartmentalization (fire protection) , genome , archaea , eukaryotic chromosome fine structure , chromatin , chromosome , genetics , chromosome segregation , function (biology) , evolutionary biology , computational biology , dna , bacteria , gene , biochemistry , enzyme

In this issue of Cell, Takemata et al. demonstrate that coalescin (ClsN), an archaeal condensin ortholog, facilitates higher-level organization of chromosomes in crenarchaea that bears greater similarity to metazoans than bacteria. Their study unravels biological function for chromosome organization in Archaea and provides insights into the evolution of eukaryotic chromosomal compartmentalization.

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