Open AccessThe Face of Chromatin Variants
Author(s) -
Andrew Flaus,
Tom OwenHughes
Publication year - 2019
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2019.08.024
Subject(s) - biology , histone , chromatin , gene isoform , genetics , chromatin remodeling , gene
A developmental program affecting human face shape is shown by Greenberg et al. (2019) to hinge on the ability to distinguish a single methyl group between two histone variant isoforms and the action of the chromatin-remodeling enzyme SRCAP. This challenges researchers to link atomic structure to a morphological defect.
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