Open AccessWhen Time Matters: An Adolescent Intervention to Prevent Adult Brain Dysfunction
Author(s) -
Sarah Canetta,
Christoph Kellendonk
Publication year - 2019
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2019.08.015
Subject(s) - biology , schizophrenia (object oriented programming) , hippocampal formation , prefrontal cortex , intervention (counseling) , neuroscience , cognition , brain function , psychiatry , psychology
Can we one day prevent mental disorders? Mukherjee et al. (2019) use a genetic mouse model of schizophrenia-risk with established abnormalities in adult hippocampal-prefrontal circuit function and cognitive behaviors to identify circuit-specific treatments during adolescence that prevent the onset of the adult deficits.
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