Open AccessWhen Fasting Gets Tough, the Tough Immune Cells Get Going—or Die
Author(s) -
Roberta Buono,
Valter D. Longo
Publication year - 2019
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2019.07.052
Subject(s) - biology , immune system , die (integrated circuit) , immunology , nanotechnology , materials science
Cycles of fasting reduce autoimmunity and activate lymphocyte-dependent killing of cancer cells, but the mechanisms remain poorly understood. Three studies in this issue of Cell begin to reveal the drastic and complex effects of fasting and severe calorie restriction on the levels and localization of different immune cells and the mechanisms responsible for them.
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