Open AccessSensory Neurons Drive Anticipatory Immunity
Author(s) -
Anna M. Trier,
Brian Kim
Publication year - 2019
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2019.07.012
Subject(s) - biology , immunity , sensory system , reflex , neuroscience , immune system , sensory neuron , immunology
Sensory neurons have recently emerged as critical mediators of immunity. Cohen et al. (2019) demonstrate that peripheral neurons utilize reflex arcs in order to rapidly condition the immune response in skin adjacent to the site of infection. This nerve reflex arc generates anticipatory immunity for more effective elimination of the pathogen if later exposed.
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