Open AccessBeginning of a New Era: Mapping the Bone Marrow Niche
Author(s) -
Ayako NakamuraIshizu,
Ben D. MacArthur,
Toshio Suda
Publication year - 2019
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2019.05.042
Subject(s) - biology , stem cell , bone marrow , stromal cell , haematopoiesis , niche , stroma , microbiology and biotechnology , hematopoietic stem cell , immunology , cancer research , biochemistry , immunohistochemistry
Baryawno et al. provide a comprehensive atlas of the mouse bone marrow stroma based on single-cell RNA-sequencing data. Their analysis reveals a taxonomy of 17 distinct cell types with diverse functions that highlights the complexity of the bone marrow stroma and paves the way for future in vivo assessment.
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