Open AccessNuclear (Bio)physics in the Embryo
Author(s) -
Stanislav Y. Shvartsman,
Matej Krajnc
Publication year - 2019
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2019.04.031
Subject(s) - biology , zygote , maternal to zygotic transition , embryo , cytoplasm , microbiology and biotechnology , contractility , evolutionary biology , computational biology , embryogenesis , endocrinology
Deneke et al. (2019) discover that dynamic interactions of cell cycle and actomyosin contractility systems synchronize nuclear cleavages, generating a cytoplasmic flow that results in a spatially uniform distribution of zygotic nuclei in the early Drosophila embryo. This work underscores the importance of self-organizing mechanisms before the onset of zygotic transcription.
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