Open AccessSelf-Assembling Nanoparticles Usher in a New Era of Vaccine Design
Author(s) -
Rino Rappuoli,
Davide Serruto
Publication year - 2019
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2019.02.008
Subject(s) - biology , virology , antigen , nanoparticle , virus , microbiology and biotechnology , nanotechnology , immunology , materials science
In this issue, Marcandalli et al. (2019) report a self-assembling nanoparticle bearing an antigen from respiratory syncytial virus. This is the first time the structure, stability, and adjuvanticity of an antigen have been rationally designed at the atomic level and incorporated in one vaccine.
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