Flaviviruses Hit a Moving Target
Author(s) -
Jonathan Braun
Publication year - 2018
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2018.10.060
Subject(s) - enteric nervous system , biology , irritable bowel syndrome , intestinal motility , intestinal microbiome , motility , interstitial cell of cajal , microbiome , rifaximin , immunology , medicine , bioinformatics , microbiology and biotechnology , neuroscience , immunohistochemistry , antibiotics
The enteric nervous system (ENS) is central to intestinal motility and a candidate target for the heterogeneous spectrum of dysmotility diseases. White et al. reveal that relapsing intestinal dysmotility occurs when partial ENS depletion by enteric neurotropic viruses is followed by functional impairment due to intermittent nonspecific intestinal inflammation.
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