Exposing a Virus Hiding in the Animal Facility | Zendy

Colin R. Parrish | Zendy

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Exposing a Virus Hiding in the Animal Facility

Author(s) -

Colin R. Parrish

Publication year - 2018

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2018.09.033

Subject(s) - parvovirus , biology , nephropathy , kidney disease , renal pathology , fibrosis , kidney , virus , virology , immunology , pathology , medicine , genetics , endocrinology , diabetes mellitus

Roediger et al. (2018) demonstrate that a kidney disease characterized by apparently spontaneous nephropathy that had been recognized in laboratory mice for many years is caused by a newly recognized virus named the mouse kidney parvovirus (MKPV). That virus appears to be widespread in mouse colonies as it is not detected by current diagnostic tools, and its recognition presents new opportunities for understanding the pathology of tubulointerstitial fibrosis.

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