Open AccessAster: A New Star in Cholesterol Trafficking
Author(s) -
Vassily I. Kutyavin,
Ajay Chawla
Publication year - 2018
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2018.09.025
Subject(s) - endoplasmic reticulum , biology , advanced spaceborne thermal emission and reflection radiometer , cholesterol , microbiology and biotechnology , biochemistry , satellite , engineering , aerospace engineering
Life evolved in an aqueous environment, necessitating the evolution of carrier proteins to shuttle lipophilic molecules within and between cells. Sandhu et. al. (2018) report the discovery of a long-sought-after cholesterol carrier protein, named Aster, which transports cholesterol from the plasma membrane to the endoplasmic reticulum.
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