Open AccessSnapShot: RNA Structure Probing Technologies
Author(s) -
Paul D. Carlson,
Molly Evans,
Angela M Yu,
Eric J. Strobel,
Julius B. Lucks
Publication year - 2018
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2018.09.024
Subject(s) - biology , rna , computational biology , snapshot (computer storage) , nucleic acid structure , genetics , gene , computer science , database
Chemical probing coupled to high-throughput sequencing offers a flexible approach to uncover many aspects of RNA structure relevant to its cellular function. With a wide variety of chemical probes available that each report on different features of RNA molecules, a broad toolkit exists for investigating in vivo and in vitro RNA structure and interactions with other molecules.
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