Structural Basis of Smoothened Activation in Hedgehog Signaling | Zendy

Pengxiang Huang | Zendy; Sanduo Zheng | Zendy; Bradley M. Wierbowski | Zendy; Youngchang Kim | Zendy; Daniel Nedelcu | Zendy; Laura Aravena | Zendy; Jing Liu | Zendy; Andrew C. Kruse | Zendy; Adrian Salic | Zendy

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Structural Basis of Smoothened Activation in Hedgehog Signaling

Author(s) -

Pengxiang Huang,

Sanduo Zheng,

Bradley M. Wierbowski,

Youngchang Kim,

Daniel Nedelcu,

Laura Aravena,

Jing Liu,

Andrew C. Kruse,

Adrian Salic

Publication year - 2018

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2018.09.003

Subject(s) - smoothened , biology , hedgehog , microbiology and biotechnology , signal transduction

(Cell 174, 312–324.e1–e16; July 12, 2018) In our paper, we reported crystal structures of sterol-activated Smoothened. It has come to our attention that we failed to cite an important contemporaneous contribution from Rohatgi and colleagues (Luchetti et al., 2016) who reported identification of cholesterol as the endogenous SMO agonist. This reference has been added online to the References and a citation added in the Introduction and the Discussion alongside the Huang et al., 2016 reference that we had already cited. We apologize to Drs Luchetti, Rohatgi, and colleagues and to the community for this breach of scholarship.

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