Two to Tango: Dialog between Immunity and Stem Cells in Health and Disease | Zendy

Shruti Naik | Zendy; Samantha B. Larsen | Zendy; Christopher Cowley | Zendy; Elaine Fuchs | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Two to Tango: Dialog between Immunity and Stem Cells in Health and Disease

Author(s) -

Shruti Naik,

Samantha B. Larsen,

Christopher Cowley,

Elaine Fuchs

Publication year - 2018

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2018.08.071

Subject(s) - biology , immunity , dialog box , stem cell , disease , virology , immunology , genetics , immune system , world wide web , medicine , computer science

Stem cells regenerate tissues in homeostasis and under stress. By taking cues from their microenvironment or "niche," they smoothly transition between these states. Immune cells have surfaced as prominent members of stem cell niches across the body. Here, we draw parallels between different stem cell niches to explore the context-specific interactions that stem cells have with tissue-resident and recruited immune cells. We also highlight stem cells' innate ability to sense and respond to stress and the enduring memory that forms from such encounters. This fascinating crosstalk holds great promise for novel therapies in inflammatory diseases and regenerative medicine.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research