Open AccessNeonate-omics: Charting the Unknown Immune Response in Early Life
Author(s) -
Madeleine F. Jennewein,
Audrey L. Butler,
Galit Alter
Publication year - 2018
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2018.08.001
Subject(s) - biology , immune system , immunity , omics , immunology , bioinformatics
The study of neonatal immunology has been hampered by lack of access to infant samples. Novel sample sparing methods and systems-wide approaches have uniquely expanded this field, demonstrating that newborn immunity varies widely but converges over the first 3 months of life. During this important time window, environmental and genetic factors impact the infant immune system and can influence lifelong immunity.
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