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Microbiome: Focus on Causation and Mechanism
Author(s) -
Michael A. Fischbach
Publication year - 2018
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2018.07.038
Subject(s) - biology , microbiome , mechanism (biology) , causation , enthusiasm , computational biology , bioinformatics , evolutionary biology , epistemology , psychology , social psychology , philosophy
There is tremendous enthusiasm for the microbiome in academia and industry. This Perspective argues that in order to realize its potential, the field needs to focus on establishing causation and molecular mechanism with an emphasis on phenotypes that are large in magnitude, easy to measure, and unambiguously driven by the microbiota.

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