Lean on Me: Cell-Cell Interactions Release TGF-β for Local Consumption Only | Zendy

Aidan J. Peterson | Zendy; Michael B. O’Connor | Zendy

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Lean on Me: Cell-Cell Interactions Release TGF-β for Local Consumption Only

Author(s) -

Aidan J. Peterson,

Michael B. O’Connor

Publication year - 2018

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2018.06.008

Subject(s) - biology , signal transduction , r smad , context (archaeology) , transcriptome , microbiology and biotechnology , neurodegeneration , cell signaling , transforming growth factor beta , computational biology , neuroscience , genetics , receptor , gene expression , gene , tgf alpha , growth factor , medicine , paleontology , disease , pathology

A new study combines detailed biochemical characterization with whole-animal genetics and computational transcriptome data mining to reveal how the LRRC33 milieu molecule imposes an exquisite level of spatial control on TGF-β signaling in the CNS.

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