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Visible Machine Learning for Biomedicine
Author(s) -
Michael Yu,
Jianzhu Ma,
Jasmin Fisher,
Jason F. Kreisberg,
Benjamin J. Raphael,
Trey Ideker
Publication year - 2018
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2018.05.056
Subject(s) - biomedicine , artificial intelligence , scopus , deep learning , machine learning , field (mathematics) , data science , face (sociological concept) , biology , computer science , medline , bioinformatics , biochemistry , social science , mathematics , sociology , pure mathematics
A major ambition of artificial intelligence lies in translating patient data to successful therapies. Machine learning models face particular challenges in biomedicine, however, including handling of extreme data heterogeneity and lack of mechanistic insight into predictions. Here, we argue for "visible" approaches that guide model structure with experimental biology.

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