Social Isolation Co-opts Fear and Aggression Circuits | Zendy

Jose Rodríguez-Romaguera | Zendy; Garret D. Stuber | Zendy

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Social Isolation Co-opts Fear and Aggression Circuits

Author(s) -

Jose Rodríguez-Romaguera,

Garret D. Stuber

Publication year - 2018

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2018.04.031

Subject(s) - aggression , neuroscience , social isolation , arousal , wakefulness , psychology , social defeat , social stress , isolation (microbiology) , biology , developmental psychology , psychiatry , bioinformatics , electroencephalography

Social isolation is a stressful condition that often leads to maladaptive behaviors. In this issue of Cell, Zelikowsky et al. find that chronic social isolation stress triggers an increase in neuronal tachykinin signaling across distinct brain regions that mediate fear and aggression, elucidating the neural basis of these maladaptive responses.

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