Open Access(IR)Factor for NAIP Expression
Author(s) -
Sivapriya Kailasan Vanaja,
Vijay Rathinam
Publication year - 2018
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2018.04.022
Subject(s) - biology , transcription factor , innate immune system , irf8 , gene , genetics , immune system , gene expression , microbiology and biotechnology
IRF8 is a master transcription factor for immune cell development. In this issue, Karki et al. reveal that IRF8 governs the constitutive expression of genes encoding for NAIP proteins that are critical for the innate immune sensing of bacteria.
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