Open AccessThe Unexpected Effects of the Combination of Antibiotics and Immunity
Author(s) -
Thomas Burke
Publication year - 2018
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2018.02.003
Subject(s) - biology , immunity , antibiotics , immunology , microbiology and biotechnology , immune system
β-lactam antibiotics and immune enzymes, including lysozyme, kill bacteria by rupturing the cell wall. Curiously, their combination can select for viable, wall-less bacteria. Kawai and colleagues describe the molecular details regarding the emergence of these forms, illustrating a novel and potentially clinically relevant mechanism by which bacteria escape killing by antibiotics.
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