Custom-Made Oocytes to Clone Non-human Primates | Zendy

José B. Cibelli | Zendy; J. B. Gurdon | Zendy

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Custom-Made Oocytes to Clone Non-human Primates

Author(s) -

José B. Cibelli,

J. B. Gurdon

Publication year - 2018

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2018.01.030

Subject(s) - somatic cell nuclear transfer , biology , somatic cell , oocyte , reprogramming , clone (java method) , cloning (programming) , microbiology and biotechnology , genetics , epigenetics , embryo , immunology , andrology , blastocyst , cell , embryogenesis , gene , medicine , computer science , programming language

In this issue of Cell, Liu et al. (2018) report the birth of two healthy cloned macaque monkeys using fetal fibroblasts. By artificially enhancing the arsenal of epigenetic modifiers in the oocyte, the authors overcome the earliest roadblocks that take place during somatic cell nuclear transfer (SCNT).

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