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Meiotic Recombination: Genetics’ Good Old Scalpel
Author(s) -
Shai Slomka,
Yitzhak Pilpel
Publication year - 2018
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2018.01.017
Subject(s) - biology , meiosis , genetics , recombination , homologous recombination , genetic recombination , evolutionary biology , gene
In the era of genome engineering, a new study returns to classical genetics to decipher genotype-phenotype relationships in unprecedented throughput and with unprecedented accuracy. Capitalizing on natural variation in yeast strains and frequent meiotic recombination, She and Jarosz (2018) dissect and map to nucleotide resolution, simple and complex determinants of diverse phenotypic traits.

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