Open AccessPlatelets, On Your Marks, Get Set, Migrate!
Author(s) -
Sarah K. Bambach,
Tim Lämmermann
Publication year - 2017
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2017.11.026
Subject(s) - biology , set (abstract data type) , platelet , computational biology , evolutionary biology , immunology , computer science , programming language
The idea that anucleate platelets display autonomous migration has long been viewed with skepticism. Gaertner et al. provide in vivo evidence that platelets undergo active migration at sites of thrombus formation and in inflamed liver sinusoids. Integrin-dependent migration allows platelets to scavenge and bundle fibrin-bound material, including intravascular bacteria.
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