SnapShot: Discovering Genetic Regulatory Variants by QTL Analysis | Zendy

Margot Brandt | Zendy; Tuuli Lappalainen | Zendy

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SnapShot: Discovering Genetic Regulatory Variants by QTL Analysis

Author(s) -

Margot Brandt,

Tuuli Lappalainen

Publication year - 2017

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2017.10.031

Subject(s) - expression quantitative trait loci , biology , snapshot (computer storage) , quantitative trait locus , computational biology , genomics , genetics , locus (genetics) , proteomics , gene expression profiling , gene , trait , evolutionary biology , gene expression , genome , genotype , single nucleotide polymorphism , computer science , programming language , operating system

Expression quantitative trait locus (eQTL) analysis is an approach for identifying how genetic variation between individuals contributes to inter-individual differences in gene expression. In this SnapShot, we describe the basic principles of eQTL analysis and its applications to diverse molecular traits of the cell measured by genomics and proteomics assays.

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