Open AccessEditing the Phenotype: A Revolution for Quantitative Genetics
Author(s) -
James A. Birchler
Publication year - 2017
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2017.09.024
Subject(s) - biology , phenotype , genetics , computational biology , evolutionary biology , gene
Quantitative trait genes have been difficult to analyze because of the subtle effects of their natural variation. Rodríguez-Leal et al. now develop a promoter-editing approach to generate a range of effective alleles for analysis, providing an avenue to investigate complex interactions among such genes.
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