TOR, the Gateway to Cellular Metabolism, Cell Growth, and Disease | Zendy

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TOR, the Gateway to Cellular Metabolism, Cell Growth, and Disease

Author(s) -

John Blenis

Publication year - 2017

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2017.08.019

Subject(s) - biology , gateway (web page) , metabolism , cellular metabolism , cell metabolism , disease , microbiology and biotechnology , cell , computational biology , genetics , biochemistry , medicine , world wide web , computer science

Michael N. Hall is this year's recipient of the Lasker Basic Medical Research Award for the identification of the target of rapamycin, TOR. TOR is a master regulator of the cell's growth and metabolic state, and its dysregulation contributes to a variety of diseases, including diabetes, obesity, neurodegenerative disorders, aging, and cancer, making the TOR pathway an attractive therapeutic target.

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