Open AccessExperimental Evolution to Study Virus Emergence
Author(s) -
Nathan D. Grubaugh,
Kristian G. Andersen
Publication year - 2017
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2017.03.018
Subject(s) - biology , virology , virus , evolutionary biology , viral evolution , genetics , genome , gene
Understanding how viruses adapt to new environments and acquire new phenotypes is critical for developing comprehensive responses to outbreaks. By studying the emergence of vaccine-derived poliovirus outbreaks, Stern et al. describe how a combination of sequence analysis and experimental evolution can be used to reveal adaptive pathways.
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