Open AccessLinking Protein and RNA Function within the Same Gene
Author(s) -
Anthony J. Szempruch,
Mitchell Guttman
Publication year - 2017
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2017.02.014
Subject(s) - biology , rna , transcription (linguistics) , gene , genetics , non coding rna , dna , gene expression , computational biology , microbiology and biotechnology , linguistics , philosophy
Exposure to ultraviolet light leads to a cell-wide DNA damage response that includes a global reduction in transcription. Williamson et al., identify a protein involved in this process as well as a noncoding RNA produced by alternative processing of RNA transcribed from the same gene that promotes recovery from the repressed state.
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