Easy Stress Relief by EZH2
Author(s) -
Supriya G. Prasanth,
Kannanganattu V. Prasanth
Publication year - 2016
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2016.11.051
Subject(s) - biology , repressor , transcription (linguistics) , gene , genetics , rna , non coding rna , function (biology) , computational biology , transcription factor , microbiology and biotechnology , linguistics , philosophy
While we are beginning to appreciate the cellular roles played by long noncoding RNAs, the function of transcripts emerging from repetitive genomic regions remains enigmatic. In this issue, Zovoilis et al. report that the polycomb protein EZH2, upon heat shock, facilitates transcription of stress-responsive genes by inducing the degradation of the transcriptional repressor B2 repeat RNA.
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