Open AccessUnwinding Limb Development
Author(s) -
Diego Villar,
Duncan T. Odom
Publication year - 2016
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2016.10.007
Subject(s) - biology , body plan , vertebrate , limb development , enhancer , evolutionary biology , underpinning , anatomy , microbiology and biotechnology , genetics , gene , embryo , transcription factor , civil engineering , engineering
The molecular mechanisms underpinning vertebrate body plan evolution are beginning to be unravelled. In this issue of Cell, Kvon et al. spectacularly demonstrate how transplanting snake-specific genetic changes found uniquely in serpent enhancers leads to limb loss in mice.
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