Timeline: Targeted Treatment of Hepatitis C Virus | Zendy

Gail Teitzel | Zendy

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Timeline: Targeted Treatment of Hepatitis C Virus

Author(s) -

Gail Teitzel

Publication year - 2016

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2016.08.066

Subject(s) - timeline , biology , hepatitis c virus , cirrhosis , virology , virus , immunology , medicine , history , archaeology

Chronic hepatitis C virus infection can cause liver cirrhosis and cancer, and early treatment options were non-specific and could be toxic. Work aimed at elucidating the viral life cycle has led to better treatment options through the development of direct-acting antivirals, as exemplified by the work of Ralf Bartenschlager, Charles Rice, and Michael Sofia who have received the Lasker∼DeBakey Clinical Medical Research Award for their work on this effort. Key events in understanding HCV replication and development of direct-acting antivirals are shown in this Timeline.

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