Timeline: Cellular Oxygen Sensing | Zendy

Lara Szewczak | Zendy

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Timeline: Cellular Oxygen Sensing

Author(s) -

Lara Szewczak

Publication year - 2016

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2016.08.065

Subject(s) - biology , timeline , oxygen transport , reactive oxygen species , oxygen , bioinformatics , physiology , computational biology , microbiology and biotechnology , immunology , chemistry , organic chemistry , archaeology , history

Since the 1950s, researchers have recognized that red blood cell numbers expand or contract as needed, according to the amount of available oxygen. The later discoveries that erythropoietin and VEGF levels adapt to oxygen levels launched a new field aimed at understanding how cells sense and respond to normal- and low-oxygen environments. The 2016 Albert Lasker Basic Medical Research Award recognizes key discoveries about this global oxygen sensing pathway and its impacts on pathogenesis, including cancer and inflammation.

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