Open AccessKidney Macrophages: Unique Position Solves a Complex Problem
Author(s) -
Miriam Berry,
Menna R. Clatworthy
Publication year - 2016
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2016.07.047
Subject(s) - biology , position (finance) , kidney , microbiology and biotechnology , computational biology , genetics , economics , finance
Immune complex-mediated diseases, such as systemic lupus erythematosus, commonly affect the kidney and determine disease prognosis. Stamatiades et al. now propose a kidney-specific mechanism for trans-endothelial transport of small immune complexes that activate strategically positioned tissue resident macrophages.
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