Seeing is Believing in Ribosome Assembly | Zendy

Jonathan R. Warner | Zendy

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Seeing is Believing in Ribosome Assembly

Author(s) -

Jonathan R. Warner

Publication year - 2016

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2016.06.055

Subject(s) - biology , ribosome , ribosomal rna , chaperone (clinical) , eukaryotic ribosome , microbiology and biotechnology , ribosomal protein , 5.8s ribosomal rna , rna , ribosome profiling , computational biology , internal ribosome entry site , genetics , gene , medicine , pathology

Many proteins have been implicated genetically and biochemically in the assembly of eukaryotic ribosomes. Now, Kornprobst et al. show us how they are put together with a cryoEM structure of the 90S processome that initiates ribosome assembly, revealing the arrangement of U3 RNA and the several UTP complexes that form a chaperone-like structure around and within the developing 40S ribosomal subunit.

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