SnapShot: Microglia in Disease | Zendy

Simon Beggs | Zendy; Michael W. Salter | Zendy

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SnapShot: Microglia in Disease

Author(s) -

Simon Beggs,

Michael W. Salter

Publication year - 2016

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2016.05.036

Subject(s) - microglia , neuroscience , biology , central nervous system , disease , autism , snapshot (computer storage) , inflammation , immunology , pathology , medicine , psychiatry , computer science , operating system

The development and maintenance of the central nervous system is dependent upon regulated, homeostatic actions of microglia, which sculpt and refine neuronal circuitry. By contrast, dysregulation of microglia contributes to the pathology of neurodevelopmental disorders such as autism spectrum disorders; neurodegenerative disorders such as Alzheimer's disease; and schizophrenia and chronic neuropathic pain.

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