Open AccessWormhole Travel for Macrophages
Author(s) -
Yasutaka Okabe,
Ruslan Medzhitov
Publication year - 2016
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2016.04.005
Subject(s) - biology , microbiology and biotechnology , macrophage , immunology , genetics , in vitro
Leukocyte recruitment is generally achieved by rapid migration of inflammatory cells out of circulation, through modified blood vessels, and into affected tissues. Now, Wang and Kubes show that macrophages can be rapidly recruited from body cavities to the liver, via a non-vascular route, where they help to coordinate tissue repair.
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