Combination Cancer Therapies with Immune Checkpoint Blockade: Convergence on Interferon Signaling | Zendy

Andy J. Minn | Zendy; E. John Wherry | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Combination Cancer Therapies with Immune Checkpoint Blockade: Convergence on Interferon Signaling

Author(s) -

Andy J. Minn,

E. John Wherry

Publication year - 2016

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2016.03.031

Subject(s) - biology , blockade , immune checkpoint , immune system , interferon , innate immune system , signal transduction , cancer , immunology , immunotherapy , cancer research , receptor , microbiology and biotechnology , genetics

Improving efficacy of immune checkpoint blockade for cancer can be facilitated by combining these agents with each other and/or with other conventional or targeted therapies. Interferon and innate immune signaling pathways in immune and tumor cells have emerged as intriguing determinants of response and resistance, often in complex and seemingly paradoxical ways.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research