Open AccessCSR-1 Slices a Balance
Author(s) -
Ruby Yu,
Danesh Moazed
Publication year - 2016
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2016.03.019
Subject(s) - argonaute , biology , gene silencing , rna interference , piwi interacting rna , microbiology and biotechnology , regulation of gene expression , gene , genetics , rna
CSR-1 is a germline-expressed C. elegans Argonaute protein essential for viability. In this issue of Cell, Gerson-Gurwitz et al. now demonstrate a role for CSR-1 and its slicer activity in downregulating the levels of maternally deposited mRNAs to fine-tune the expression of proteins with critical roles in embryonic cell divisions.
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