Open AccessInsulin Signaling in a Bit of a Jam
Author(s) -
Vassily I. Kutyavin,
Ajay Chawla
Publication year - 2016
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2016.03.012
Subject(s) - biology , inflammation , insulin , signal transduction , microbiology and biotechnology , bioinformatics , cancer research , immunology , endocrinology
In this issue of Cell, Okin and Medzhitov report that sustained inflammation promotes hyperglycemia by targeting the mevalonate pathway. This represents an important step forward in understanding the mechanisms underlying the association between chronic low-grade inflammation and disruption of normal tissue functions in metabolic diseases.
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