From the Beauty of Genomic Landscapes to the Strength of Transcriptional Mechanisms
Author(s) -
Gioacchino Natoli
Publication year - 2016
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2016.03.011
Subject(s) - biology , computational biology , enhancer , chromatin , gene , genome , transcriptional regulation , genetics , context (archaeology) , transcription factor , genomics , promoter , set (abstract data type) , regulation of gene expression , evolutionary biology , data science , gene expression , computer science , paleontology , programming language
Genomic analyses are commonly used to infer trends and broad rules underlying transcriptional control. The innovative approach by Tong et al. to interrogate genomic datasets allows extracting mechanistic information on the specific regulation of individual genes.
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