Open AccessA New Way to Diversify Antibodies by DNA Transposition
Author(s) -
Davide F. Robbiani,
Michel C. Nussenzweig
Publication year - 2016
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2016.01.031
Subject(s) - biology , transposition (logic) , genetics , dna , antibody , computational biology , virology , philosophy , linguistics
While searching for new therapeutics against malaria, Lanzavecchia and colleagues discovered that antibodies can be diversified by DNA sequences encoded outside of antibody genes.
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