The Importance of Timing | Zendy

Richard S. Mann | Zendy; Clare E. Howard | Zendy

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The Importance of Timing

Author(s) -

Richard S. Mann,

Clare E. Howard

Publication year - 2016

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2016.01.010

Subject(s) - biology , mechanism (biology) , transcription factor , transcription (linguistics) , computational biology , genetics , microbiology and biotechnology , nervous system , evolutionary biology , neuroscience , gene , philosophy , linguistics , epistemology

Building a nervous system requires a precise sequence of genetic transitions, mediated in part by the temporal and spatial regulation of transcription factors. Quan et al. add to our understanding of this regulation by describing an evolutionarily conserved post-translational mechanism that rapidly extinguishes proneural protein activity in neural precursors.

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