Open AccessEpigenetic ON/OFF Switches for Obesity
Author(s) -
Carmelo Quarta,
Robert Schneider,
Matthias H. Tschöp
Publication year - 2016
Publication title -
cell
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 26.304
H-Index - 776
eISSN - 1097-4172
pISSN - 0092-8674
DOI - 10.1016/j.cell.2016.01.006
Subject(s) - biology , epigenetics , polyphenism , obesity , energy metabolism , epigenesis , genetics , bioinformatics , evolutionary biology , dna methylation , gene , endocrinology , phenotypic plasticity , gene expression
Heritable epigenetic mechanisms might contribute to the worldwide increase in the prevalence of obesity. Dalgaard et al. identify an epigenetic molecular switch that controls body weight control. The discovery suggests the existence of mammalian polyphenism in energy metabolism and might have implications for strategies to limit the obesity epidemic.
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