Alpha and Beta Type 1 Interferon Signaling: Passage for Diverse Biologic Outcomes | Zendy

Cherie Ng | Zendy; Juan L. Mendoza | Zendy; K. Christopher García | Zendy; Michael B. A. Oldstone | Zendy

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Alpha and Beta Type 1 Interferon Signaling: Passage for Diverse Biologic Outcomes

Author(s) -

Cherie Ng,

Juan L. Mendoza,

K. Christopher García,

Michael B. A. Oldstone

Publication year - 2016

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2015.12.027

Subject(s) - biology , interferon , interferon type i , beta (programming language) , alpha interferon , cascade , interferon gamma , alpha (finance) , immunology , interferon beta , virology , cytokine , computer science , programming language , medicine , construct validity , chemistry , nursing , chromatography , patient satisfaction

Type I interferon (IFN-I) elicits a complex cascade of events in response to microbial infection. Here, we review recent developments illuminating the large number of IFN-I species and describing their unique biologic functions.

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