SnapShot: Interferon Signaling | Zendy

Kwan T. Chow | Zendy; Michael Gale | Zendy

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SnapShot: Interferon Signaling

Author(s) -

Kwan T. Chow,

Michael Gale

Publication year - 2015

Publication title -

cell

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 26.304

H-Index - 776

eISSN - 1097-4172

pISSN - 0092-8674

DOI - 10.1016/j.cell.2015.12.008

Subject(s) - biology , snapshot (computer storage) , interferon , innate immune system , receptor , signal transduction , acquired immune system , immunity , microbiology and biotechnology , immunology , immune system , computational biology , genetics , computer science , operating system

Interferons (IFNs) are crucial cytokines of antimicrobial, antitumor, and immunomodulatory activity. The three types of IFN (I, II, and III) are classified by their receptor specificity and sequence homology. IFNs are produced and secreted by cells in response to specific stimuli. Here, we review the subsequent IFN signaling events occurring through unique receptors leading to regulation of gene expression for modulation of innate and adaptive immunity. To view this SnapShot, open or download the PDF.

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